Just ran across this project called CableSwig.
It seems to be a hybrid solution for generating wrappers that uses GCC-XML to parse C++ and generate interface description files that SWIG can understand.  It then uses SWIG to finish the job.

http://www.itk.org/HTML/CableSwig.html

ITK is using it to wrap their extensive (and template-heavy) C++ codebase for Python and Tcl.

Might be worth taking a gander at for folks working on wrapping various Uber C++ libraries.

--bb